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Selective Androgen Receptor Modulator

RAD-140

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BlendsPeptidesResearch chemicals

A selective androgen receptor modulator (SARM) studied for its potential to support lean muscle growth, strength, and body recomposition in preclinical research models. Premium Research Compound.

Original price was: $109.99.Current price is: $98.99.

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How RAD-140 Works

The Science, Simplified

Selective Androgen Receptor Modulation

RAD-140 (Testolone) is a non-steroidal Selective Androgen Receptor Modulator (SARM) designed to bind androgen receptors in muscle and bone with high affinity and selectivity.
Key insight: It selectively activates androgen receptors in skeletal muscle and bone tissue while showing minimal activity in non-target tissues like prostate, skin, and scalp. This tissue-selective behavior allows strong anabolic signaling with reduced androgenic side effects compared to traditional testosterone-based compounds.
GE
Primary

Gene Expression

Epigenetic Modulation

Upregulates 59% of affected genes Activates 47 DNA repair genes Suppresses inflammatory pathways

COL
Strongest

Gene Expression

Epigenetic Modulation

Upregulates 59% of affected genes Activates 47 DNA repair genes Suppresses inflammatory pathways

Cu²⁺
Supportive

Gene Expression

Epigenetic Modulation

Upregulates 59% of affected genes Activates 47 DNA repair genes Suppresses inflammatory pathways

Anabolic Protein Synthesis & Muscle Preservation

RAD-140 enhances muscle-building and anti-catabolic pathways through androgen receptor activation.

Key insight: Research shows increased protein synthesis, improved nitrogen retention, and enhanced cellular muscle signaling. This leads to improved lean mass development and reduced muscle breakdown, especially during calorie deficit or high training stress conditions.

Performance & Recomposition Effect

RAD-140 is widely studied for its ability to improve body composition and physical performance.

Key insight: Observational data shows rapid strength increases within weeks, improved training output, and noticeable lean mass gain within 3–6 weeks, often resulting in visible recomposition effects where fat loss appears secondary to muscle gain.

Wrinkle Reduction Comparison

Safety Profile from Research

What clinical studies report

RAD-140 is an investigational SARM studied in early clinical trials and preclinical research models.

🧿 Common Digestive Issues

70–85%

Testosterone suppression

mild

65–80%

HDL cholesterol reduction

mild

10–25%

Liver enzyme elevation

mild

Safety Advantage

Tissue Selectivity

  • Tissue Selectivity: Preferential activity in muscle and bone tissue, Minimal direct stimulation of prostate tissue in research models, Reduced estrogenic side effects as it does not aromatize
  • Non-Aromatizing: Does not convert into estrogen, No estrogen-related effects such as water retention or gynecomastia in studies
  • Oral Stability: High oral bioavailability, Once-daily dosing supported by ~16–20 hour half-life

📊 Discontinuation Rates

🚫 Trial Exclusions

⚡ Regulatory Status

💡 Researcher Notes

Compound Information

Technical specifications for each component

🔬 Molecular Profile

What Is RAD-140?

Full Name

Testolone (RAD-140)

Category

Selective Androgen Receptor Modulator

Type

Non-steroidal androgen receptor agonist

Chemical Formula

C20H16ClN5O2

CAS Number

1182367-47-0

Target

High-affinity androgen receptor agonist in muscle and bone

PubChem Database

🧊 Storage Requirements

Stability Information

RAD-140 (Testolone) is a synthetic non-steroidal selective androgen receptor modulator developed for research into muscle wasting conditions and age-related sarcopenia.

Stability Information

Store in a cool, dry, dark environment

Capsule Form

15–30°C

storage temperature recommended

Shelf Life

Stable for 2+ years

if protected from UV light

Humidity

Keep in airtight container to prevent degradation

📊 Physical Properties

Development History

RAD-140 (Testolone) is a synthetic non-steroidal selective androgen receptor modulator developed for research into muscle wasting conditions and age-related sarcopenia.

Classification

Selective Androgen Receptor Modulator (SARM)

Clinical Stage

Phase I/II (Breast Cancer research)

US Status

Investigational research compound

Target AR

High Affinity / Agonist in Muscle/Bone

Primary Focus

Muscle growth / Strength improvement

Original discovery

Frequently Asked Questions

Common questions about RAD-140

No. While it produces effects similar to anabolic steroids, it is chemically distinct. Steroids are synthetic versions of hormones that affect receptors throughout the entire body. Red-140 is a SARM, which is designed to be "selective," focusing its activity primarily on muscle and bone while avoiding most of the systemic side effects associated with steroids
In research models, Red-140 is known to suppress natural hormone production. This is often referred to as "suppression" rather than a total "shutdown" (which is more common with stronger steroids), but the body's natural testosterone levels will temporarily decrease while the compound is active.
The name "Testolone" is a nod to its ability to mimic the anabolic (muscle-building) effects of testosterone. However, in the scientific community, it is more commonly referred to by its developmental code, RAD-140, or its clinical name, Vosilasarm.
Research indicates that Red-140 has a relatively long half-life for a SARM, estimated at roughly 60 hours. This means it can take several days for the compound to fully clear the system after the final dose is administered.
Red-140 is legal to purchase as an investigational research chemical in most countries, including the US. However, it is not FDA-approved for human consumption, is not a legal dietary supplement, and is banned by all major sporting organizations.

Sources & References

Peer-reviewed research

  • Important Research Notice

Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

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